| Date | Grid | Clue | Author | Editor |
| Mon, Jun 19, 2023 | 48A | Shelfmate of Aleve and Advil | David Liben-Nowell | Shortz |
| Sat, Nov 26, 2022 | 22D | Pain reliever option | Kanyin Ajayi | Shortz |
| Sat, Aug 29, 2020 | 41A | This will help ease the pain | Michael Hawkins | Shortz |
| Tue, May 27, 2014 | 28A | Aleve alternative | James Tuttle | Shortz |
| Sat, Nov 19, 2011 | 32A | Severe Allergy brand | Allan E. Parrish | Shortz |
| Tue, Apr 24, 2007 | 26D | Popular reliever of aches | Brendan Emmett Quigley | Shortz |
| Sat, Dec 10, 2005 | 58A | Acetaminophen brand | Henry Hook | Shortz |
| Tue, May 11, 2004 | 42D | Aspirin alternative | Lee Glickstein and Nancy Salomon | Shortz |
| Wed, Apr 21, 2004 | 24A | Advil alternative | Michael Shteyman | Shortz |
| Sat, Mar 17, 2001 | 42D | Product in a 1982 recall | Rich Norris | Shortz |